Benjamin FOURNIER

DDS, PhD, PU-PH - Service d’Odontologie Hôpital Rothschild - APHP. Centre de Référence O-RARES

WP3

TRADUCTION CLINIQUE

Universite Paris Cité

UMRS 1138 Les Cordeliers

Pôles d’activités

Nous analysons le phénotype des fibroblastes et cellules souches spécifiques de la mâchoire qui contribueraient aux propriétés uniques de guérison ad integrum de la gencive.
Nous étudions aussi le profil spécifique des ostéoblastes oraux pour comprendre les différences de comportement de l’os des mâchoires.
Nos études testent des traitements innovants pour la reconstruction osseuse et des tissus mous.
Les variations géniques associées à des maladies génétiques orales nous permettent de comprendre leurs impacts à travers le phénotype de nos patients et la culture cellulaire (collection biologique).

Projets

Cicatrisation Orale in vitro au in vivo,
Signature des cellules souches orales et de la matrice extracellulaire associée
Collaboration Biomatériaux UQ iTEAM (Australie, Brisbane) et Urb2i (UPC)
H2020 MaxiBone (B Gogly)

Publications récentes

Decellularized extracellular matrix derived from dental pulp stem cells promotes gingival fibroblast adhesion and migration.BMC Oral Health. 2024 Oct 1;24(1):1166. doi: 10.1186/s12903-024-04882-7.PMID: 39354504
Fabrication of 3D bioactive melt electrowriting composite scaffold with high osteogenic potential. Colloids Surf B Biointerfaces. 2024 Sep 26;245:114270. doi: 10.1016/j.colsurfb.2024.114270. PMID: 39357390
Cathepsin C in health and disease: from structural insights to therapeutic prospects..J Transl Med. 2024 Aug 20;22(1):777. doi: 10.1186/s12967-024-05589-7.PMID: 39164687
Biomimetic Surface Nanoengineering of Biodegradable Zn-Based Orthopedic Implants for Enhanced Biocompatibility and Immunomodulation. Advanced Foctional Materials , September 2024, https://doi.org/10.1002/adfm.202410033.
Root resorptions induced by genetic disorders: A systematic review. Oral Dis. 2024 Sep. doi: 10.1111/odi.14942. PMID: 38566363
Oral health-related quality of life in Fanconi anemia: a cross-sectional study. .Support Care Cancer. 2024 Aug 6;32(9):571. doi: 10.1007/s00520-024-08777-9.PMID: 39105977
MSCs-Derived Decellularised Matrix: Cellular Responses and Regenerative Dentistry. Int Dent J. 2024 Jun;74(3):403-417. doi: 10.1016/j.identj.2024.02.011. Epub 2024 Mar 16. PMID: 38494389
Human dental pulp stem cells derived extracellular matrix promotes mineralization via Hippo and Wnt pathways. Sci Rep. 2024 Mar 21;14(1):6777. doi: 10.1038/s41598-024-56845-1. PMID: 38514682
Oral cancer and oral potentially malignant disorders in patients with Fanconi anemia – A systematic review. Oral Oncol. 2024 Feb. doi: 10.1016/j.oraloncology.2024.106699. PMID: 38309198
[Oral mesenchymal cells, a specific niche, from development to regeneration].Med Sci (Paris). 2024 Jan. doi: 10.1051/medsci/2023191. Epub 2024 Feb 1.PMID: 38299899 French.
Leukemia/lymphoma oral infiltration and its impact on disease outcomes: A Brazilian study. Oral Dis. 2023 Oct. doi: 10.1111/odi.14452. Epub 2022 Dec 8.PMID: 36421050
Oro-dental phenotyping and report of three families with RELT-associated amelogenesis imperfecta. Eur J Hum Genet. 2023 Sep. doi: 10.1038/s41431-023-01440-7. PMID: 37670079
Oral phenotype of Singleton-Merten syndrome : a systematic review illustrated with a case report. Frontiers in Genetics. 2022. PMID: 35754802
Efficient isolation of human gingival stem cells in a new serum-free medium supplemented with platelet lysate and growth hormone for osteogenic differentiation enhancement. Stem Cell Res Ther. 2022.PMID: 35337377
Transcriptional Regulation of Jaw Osteoblasts: Development to Pathology. J Dent Res. 2022. PMID: 35148649
The utilisation of resolvins in medicine and tissue engineering; Acta Biomater. 2022. PMID: 34875358
Extracellular Matrix Derived from Dental Pulp Stem Cells Promotes Mineralization. Front Bioeng Biotechnol. 2022 . PMID: 35155398
PTEN regulates proliferation and osteogenesis of dental pulp cells and adipogenesis of human adipose derived stem cells: Oral Dis. 2021. PMID: 34558757

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Benjamin FOURNIER

WP3

TRADUCTION CLINIQUE

LAUREATS FHUDDS DE L’AAP EMERGENCE Benjamin FOURNIER WP3, Marie Joséphine CRENN

Benjamin FOURNIER porteur de l’axe Regeneration, Healing and Oral Cells

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